Connective tissue diseases associated with interstitial lung disease (CTD-ILD) is often found to be prone to progressive pulmonary fibrosis (PPF). However, clinical understanding of how to manage PPF in CTD-ILD patients is still limited. How to standardize the treatment of this group of patients is also a common clinical problem that doctors are often faced. Therefore, Interstitial Lung Disease Group, Committee on Respiratory and Critical Care Medicine of Sichuan Medical and Health Care Promotion Institute invited experts in ILD related fields to form a consensus compilation group. Five aspects of content were finally determined according to clinical collection problems and expert discussions. The relevant contents mainly include the high risk factors of PPF in CTD-ILD, clinical manifestations and diagnosis, disease evaluation, follow-up management and treatment. Based on evidence-based evidence such as domestic and foreign guidelines and clinical research data, after many discussions and voting, 9 recommendations were formed. The “Expert Consensus on Clinical Management of CTD-ILD patients with PPF Performance in Sichuan Province” was jointly formulated. The aim is to improve the clinical understanding of CTD-ILD with PPF manifestations, provide the basis for clinical decision-making and management, and improve the level of clinical treatment.