Prostate is an important organ of male genitourinary system. With the aggravation of social aging, the incidence rate of prostate diseases has increased year by year. Among the diseases, benign prostatic hyperplasia (BPH) seriously reduces the quality of life of elderly men. BPH can cause lower urinary tract symptoms (LUTS), mainly including frequent urination, urgency, difficulty urinating, etc. These bring a heavy disease burden to patients. The detrusor overactivity (DO) has a higher incidence rate in patients with BPH. This article reviews the current research status of DO and BPH, including epidemiological, diagnostic and therapeutic advances as well as related pathogenesis studies.